Job opening - 大分子ADC工艺副主任 in 上海
【岗位职责】 1.主导项目 ADC 偶联工艺开发：运用前沿方法（如单因素试验法 OFAT、实验设计法 DoE）规划、设计并实施实验；负责偶联工艺条件的筛选、优化与确认，以确保偶联效率和产品均一性。 2.主导项目 ADC 纯化工艺开发：规划、设计并实施实验；负责 ADC 纯化工艺的开发与优化，包括组合设计亲和层析、离子交换层析、疏水作用层析、超滤/脱盐等纯化单元操作，以确保有效去除游离毒素并提升产品纯度。 3.主导项目 ADC 工艺放大：组织小试、中试与 GMP 生产之间的差距分析（Gap Analysis）；组织编写与审核技术转移（Tech Transfer）文件，推动工艺从研发向中试及 GMP 生产的平稳转移。 4.文档编写与审核：起草并审核非 G...
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